Incidence and Clinical outcome of ovarian neoplastic tumors in pregnancy

Abstract

Objective: The purpose of this study was to review patients diagnosed with
ovarian cancer in pregnancy and to assess their incidence, the effectiveness of
the available methods of treatment and prognosis of these tumors.
Methods: A review of 11 women diagnosed to have cancer of the ovary
associated with pregnancy who delivered at a tertiary care institute between
Jan 2013 to Dec 2016. The clinical presentation, time and mode of diagnosis,
treatment, pregnancy outcome and maternal survival were noted. The role and
effect of surgery and chemotherapy on maternal and fetal outcome was noted.
Results: The incidence of ovarian carcinoma associated with pregnancy in this
study was 0.265 per 1000 deliveries. Out of these women 63.6% (7/11) were
primigravidas. 45.45% (5/11) women were asymptomatic at the time of
presentation and diagnosed on routine ultrasonography. 7 patients had ovarian
epithelial malignant neoplasia. Fetal survival rate was 81.81%.
Conclusions: Ovarian tumors in pregnancy are usually diagnosed early due to
frequent routine examinations. Epithelial tumors constitute a majority of
ovarian carcinomas. The surgical staging and management should follow the
standard protocol, since outcome depends on the stage of lesion. Early
diagnosis and prompt treatment offers the best prognosis for the patient